Searchable abstracts of presentations at key conferences in endocrinology

ea0070oc9.6 | Reproductive and Developmental Endocrinology | ECE2020

Testosterone replacement therapy of opioid induced male hypogonadism improved body composition but not pain perception A double-blinded, randomized and placebo-controlled trial

Glintborg Dorte , Bjarke Vægter Henrik , Lehmann Christensen Louise , Bendix Emma , Graven-Nielsen Thomas , Andersen Per Grunwald , Andersen Marianne

Background: Hypogonadism is prevalent during opioid treatment, but the effect of testosterone replacement treatment (TRT) on body composition, pain perception, and adrenal function is unclear.Purpose: To measure changes in body composition, pain perception, quality of life and adrenal function after TRT or placebo in opioid treated men with chronic non-malignant pain.Methods: Double-blinded, placebo-controlled study in 41 men (&#62...

ea0090p19 | Adrenal and Cardiovascular Endocrinology | ECE2023

RESCUE: Effect of supplemental hydrocortisone during stress in glucocorticoid-induced adrenal insufficiency; A study protocol for a multicentre, randomised, double blinded, placebo-controlled clinical trial

Willemoes Borresen Stina , Boggild Hansen Simon , Al-Jorani Hajir , Sofie Bislev Lise , Bue Bjorner Jakob , Brun Boesen Victor , Lehmann Christensen Louise , Fenger Dreyer Anja , Glintborg Dorte , Christian Jensen Richard , Thurmann Jorgensen Nanna , Klose Marianne , Louise Lund Marie , Stankovic Jelena , Tei Randi , Watt Torquil , Otto Lunde Jorgensen Jens , Skovsager Andersen Marianne , Feldt-Rasmussen Ulla

Background: Long-term, low-dose prednisolone treatment (≤5mg/day) is associated with adrenal insufficiency in >33% of patients. Nevertheless, the clinical consequences of glucocorticoid-induced adrenal insufficiency in patients receiving ongoing low-dose glucocorticoid treatment are unknown. Current clinical guidelines do not recommend routine evaluation of adrenal function during low-dose glucocorticoid treatment, and patients are not routinely instructed to increase gl...

ea0090p564 | Adrenal and Cardiovascular Endocrinology | ECE2023

Glucocorticoid-induced adrenal insufficiency: Identification of diagnostic and prognostic biomarkers based on two randomized controlled trials - REFINE

Boggild Hansen Simon , Fenger Dreyer Anja , Willemoes Borresen Stina , Al-Jorani Hajir , Sofie Bislev Lise , Brun Boesen Victor , Lehmann Christensen Louise , Glintborg Dorte , Christian Jensen Richard , Thurmann Jorgensen Nanna , Klose Marianne , Louise Lund Marie , Stankovic Jelena , Tei Randi , Watt Torquil , M Stewart Paul , Andersen Marianne , Feldt-Rasmussen Ulla , Otto Jorgensen Jens

Background: The risk and course of glucocorticoid-induced adrenal insufficiency (GIA) are unclear and current evidence is retrospective and based on small and selected study populations. However, the prevalence of glucocorticoid use is at least 3 %, which underscores the need for unbiased and prospective assessment of the prevalence and clinical consequences of GIA.Objectives: To identify biomarkers of GIA as regards diagnosis, prognosis and responsivene...

ea0090p437 | Pituitary and Neuroendocrinology | ECE2023

Acromegaly management in the Scandinavian countries – a DELPHI consensus survey

Arlien-Soborg Mai C. , Dal Jakob , Heck Ansgar , Stochholm Kirstine , H Nielsen Eigil , Feltoft Claus , Krogh Rasmussen AEse , Feldt-Rasmussen Ulla , Andreassen Mikkel , Klose Marianne , Leo Nielsen Torben , Andersen Marianne , Lehmann Christensen Louise , Krogh Jesper , Jarlov Anne , Lyngvi Fougner Stine , Nermoen Ingrid , Bollerslev Jens , Oksnes Marianne , Dahlqvist Per , Olsson Tommy , Berinder Katarina , Hoybye Charlotte , Petersson Maria , AEkerman Anna-Karin , Wahlberg Jeanette , Ekman Bertil , Eden Engstrom Britt , Johannsson Gudmundur , Ragnarsson Oskar , Agusta Sigurjonsdottir Helga , Burman Pia , Otto Jorgensen Jens

Background: Acromegaly is associated with increased morbidity and mortality if left untreated. The therapeutic options include surgery, medical treatment, and radiotherapy. Guidelines regarding treatment algorithms and follow-up vary considerably.Aim: To evaluate consensus on the treatment and follow-up of acromegaly in the Scandinavian countries.Methods: To map the landscape of acromegaly management in the Scandinavian countries, ...